ATLANTA @ SAN FRANCISCO (SF -2.5, 47.5) NFL ODDS, NFL PREDICTIONS, NFL PREVIEWS Falcons vs 49ers Free Pick, NFL Free Picks, NFL Predictions 10/19/25 FALCONS @ 49ERS 10/19/25 The Atlanta Falcons, who are led by the best defense in the league, will try to win three games in a row tonight when they travel to Santa Clara, California, to play the struggling San Francisco 49ers.   Atlanta (3-2) has defeated the Buffalo Bills and Washington Commanders at home to win back-to-back gam