Indiana vs Ohio State (OSU -4, 48.5) CFB ODDS, CFB PREDICTIONS, CFB PREVIEWS Indiana vs Ohio State, CFB Picks, CFB Free Picks, CFB Predictions 12/06/25 INDIANA vs OHIO STATE – LUCAS OIL STADIUM – INDIANAPOLIS, IN – 8PM EDT SATURDAY We got an amazing matchup between two juggernauts on Saturday night between the #1 Ohio St Buckeyes and the #2 Indiana Hoosiers at Lucas Oil Stadium in Indianapolis, Indiana.  When doing a comparison of these elite squads, numerically you have to g